As interest in potable water reuse intensifies among municipal utilities, state and federal governments, researchers, and supporting organizations, significant effort has been focused on technical objectives related to ensuring system performance and reliability, documenting contaminant removal and public health protection, and reducing project costs. These efforts are paying off. Utilities in certain water-stressed regions are implementing successful water reuse projects, particularly in states with a long history of innovative water projects (e.g., California, Texas). Many states where interest in potable reuse is growing (e.g., Colorado, Oklahoma, North Carolina, Florida) could benefit from the experience and insights of those on the leading edge as they develop the expertise and mechanisms necessary to plan, regulate, and manage water reuse systems.