The BizNGO Chemical Alternatives Assessment Protocol is a decision framework for substituting chemicals of concern to human health or the environment with safer alternatives. It describes a process for identifying alternatives to a chemical of concern, screening out equally hazardous alternatives, and selecting an alternative that is technically and economically viable and does not have the potential for causing significant environmental or human health impacts.

GreenScreen for Safer Chemicals. A globally recognized tool that identifies hazardous chemicals and safer alternatives.

The Design for the Environment (DfE) Program at the U.S. Environmental Protection Agency developed the Alternatives Assessment Criteria for Hazard Evaluation as a transparent tool for evaluating and differentiating among chemicals based on their human health and environmental hazards. The Criteria are applied in all of DfE Alternatives Assessments and can be used by other organizations.

The Sustainable Futures program provides the public with educational training workshops on chemical screening approaches and the use of EPA's computerized models and tools developed under the Toxic Substances Control Act (TSCA).